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RMRC No. RMRC13343 Order
Strain/Stock Designation FVB/N-Tg(PGK-HSPD1)Wfs/Narl
Status
EM| (Cryopreserved Embryos)
Availability Level4
Pricing (Embryos) 　Industry：11,105NTD　Academia: 7,775NTD　NSTC: 5,415NTD
(Cryo Recovery) 　Industry：20,815NTD　Academia: 13,880NTD　NSTC: 13,880NTD
Last Update Date 2018/1/22
Analysis Data
  • Description
  • Genes &
    alleles
  • Phenotype
  • Health &
    husbandry
  • References
  • Specific Term
    and Conditions
  • Construct map
Species ： laboratory mouse
Strain Type ： COI (coisogenic strain),MSR (mutant strain)
Mutant Type ： TG (Transgenic)
Other Names ：
Background Strain ： FVB/N
Strain Description ：
1. 
The construct carried transgene was injected into fertilized embryos harvested from FVB/N 
 mice.
2.  This strain overexpressed Human HSPD1 driven by human phosphoglycerate kinase promoter.
3. 
There was no significant  difference in body weight and serum biochemistry profiles between   
 this strain and wild type.
4. 
Articular condrocytes and synovial cells strongly expressed HSPD1. Articular condrocytes density and proliferating activity were significantly increased.
5.  Articular cartilage in the media tibia plateau is thicker in this strain.
Depositor ：
Wang, Feng-Sheng / 王逢興
Email ： wangfs@ms33.hinet.net
Allele Symbol ： Tg(PGK-HSPD1)Wfs
Allele Name ： transgenic insertion 9, Wang Feng-Sheng
Allele Description ：
Strain of Origin ： FVB/N
Gene Symbol ： HSPD1
Gene Name ： heat shock protein 1 (chaperonin)
Chromosome ： UN
Genotyping Method ： Download            
Genotyping NLAC ：            
Research Application ：
Apoptosis Immunology and Inflammation
Metabolism Diabetes and Obesity
Genetics Research
Construction Technologies ： No
Animal Health Reports ：
Colony Maintenance
Breeding & Husbandry 		： No
Colony Maintenance
Mating System 		： homo x homo
References ： PubMed ID: 27118120

Specific Terms of Use ：
有特別規定
本生物材料僅限使用於學術研究。寄存者對於分讓申請人使用本材料 所獲得之研究成果，不主張任何專利、智慧財產權及其他財產權
DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of BIOLOGICAL RESOURCE for academic research purpose.
分讓申請人公開發表使用本材料所獲得之論文或其他研究成果時，應引用下述已發表之論文： J Mol Med (Berl). 2016, 94(7):755-69
Should the use of this material result in one or more scientific
publication(s) the recipient agrees to cite the paper(s)： J Mol Med (Berl). 2016, 94(7):755-69
分讓申請人公開發表使用本材料所獲得之論文或其他研究成果時，應揭露並致謝本材料係由Core Lab. for Phenomics and Diagnostics, CGMH所提供
Should the use of this material result in one or more scientific publication(s) the Recipient Investigator agrees to mention and acknowledge Core Lab. for Phenomics and Diagnostics, CGMH
Construct Map ：
 
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