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RMRC No.

RMRC13205

Order

Strain/Stock Designation

NOD-Tg(INS-anti-Tnfrsf9scFv)Sytwu

Status

EM| (Cryopreserved Embryos)

Availability

Level4

Pricing

(Embryos) 　International：560USD
(Cryo Recovery) 　International：760USD

Last Update Date

2014/10/21

Analysis Data

Description
Genes &
alleles
Phenotype
Health &
husbandry
References
Specific Term
and Conditions
Construct map

Species

：

laboratory mouse

Strain Type

：

COI (coisogenic strain),MSR (mutant strain)

Mutant Type

：

TG (Transgenic)

Other Names

：

Background Strain

：

NOD/Sytwu

Strain Description

：

1. Transgene contains an engineered single-chain anti- Tnfrsf9 Fv, transmembrane domain of the IgG-like C-type domain, cytoplasmic tail of murine CD80, under the human insulin promoter
2. Earlier onset of severe diabetes and insulitis

Depositor

：

Huey-Kang Sytwu

司徒惠康

：

Allele Symbol	：	Tg(INS-anti-Tnfrsf9scFv)Sytwu

Allele Name	：	Target mutation, Huey-Kang Sytwu

Allele Description	：






Strain of Origin	：	NOD/Sytwu

Gene Symbol	：	Tnfrsf9

Gene Name	：	tumor necrosis factor receptor superfamily, member 9

Chromosome	：	UN






Genotyping Method	：	Download
Genotyping NLAC	：

Research Application

：

Immunology and Inflammation

Diabetes and Obesity

Construction Technologies

：

Animal Health Reports	：

Colony Maintenance Breeding & Husbandry	：

Colony Maintenance Mating System	：	hetero/hemi x wild type

References

：

PubMed ID: 14599849

Specific Terms of Use

：

有特別規定
本生物材料僅限使用於學術研究。寄存者對於分讓申請人使用本材料所獲得之研究成果，不主張任何專利、智慧財產權及其他財產權
DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of BIOLOGICAL RESOURCE for academic research purpose.

分讓申請人公開發表使用本材料所獲得之論文或其他研究成果時，應引用下述已發表之論文： Anti-4-1BB-based immunotherapy for autoimmune diabetes: lessons from a transgenic non-obese diabetic (NOD) model.

Should the use of this material result in one or more scientific
publication(s) the recipient agrees to cite the paper(s)： Anti-4-1BB-based immunotherapy for autoimmune diabetes: lessons from a transgenic non-obese diabetic (NOD) model.

分讓申請人公開發表使用本材料所獲得之論文或其他研究成果時，應揭露並致謝本材料係由Dr. Huey-Kang Sytwu所提供

Should the use of this material result in one or more scientific publication(s) the Recipient Investigator agrees to mention and acknowledge Dr. Huey-Kang Sytwu

分讓申請人向國研院動物中心國家實驗鼠種原庫(NLAC-RMRC)申請本材料時，應附上寄存人簽名之授權分讓同意書作為附件；NLAC- RMRC 在取得寄存人書面同意後，始進行此材料之分讓。
The recipient should obtain a written consent from the depositor of the BIOLOGICAL RESOURCE, prior to NLAC-RMRC accepting the material distribution request.
Depositor Email:

Construct Map

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