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RMRC No. RMRC13312 Order
Strain/Stock Designation B6.129-Cdk12tm1Fmj/Narl
Status
EM| (Cryopreserved Embryos)
Availability Level4
Pricing (Embryos) 　International：560USD
(Cryo Recovery) 　International：760USD
Last Update Date 2017/9/21
Analysis Data
  • Description
  • Genes &
    alleles
  • Phenotype
  • Health &
    husbandry
  • References
  • Specific Term
    and Conditions
  • Construct map
Species ： laboratory mouse
Strain Type ： MSK (mutant stock),CON (congenic strain)
Mutant Type ： TM (Target Mutation)
Other Names ：
Background Strain ： C57BL/6
Strain Description ：
1.  The targeting vector containingCdk12 sequences between exon 3 and exon 4 flanked by loxP was electroporated into R1 embryonic stem cells.
2.  The chimera derived from R1 ES cells were bred with C57BL/6J and kept in C57BL/6 background for 6 generation at least.
3.  The exon 3 and exon 4 of Cdk12 gene in this strain are loxP-flanked.
4.  The breeding scheme used in this strain is homozygous mutant (fl/fl) x homozygous mutant (fl/fl).
Depositor ：
Ming-Ji Fann / 范明基
Email ： mjfann@ym.edu.tw
Allele Symbol ： Cdk12tm1Fmj
Allele Name ： cyclin-dependent kinase 12, target mutation 1, Ming-Ji Fann
Allele Description ：
Strain of Origin ： 129
Gene Symbol ： Cdk12
Gene Name ： cyclin-dependent kinase 12
Chromosome ： 11
Genotyping Method ： Download            
Genotyping NLAC ：            
Research Application ：
Apoptosis Cancer
Cell and Developmental Biology Neurobiology Research
Genetics Research
Construction Technologies ：
Cre-lox system
Animal Health Reports ：
Colony Maintenance
Breeding & Husbandry 		：
Colony Maintenance
Mating System 		： homo x homo
References ： PubMed ID: 24999027
PubMed ID: 27073218
Specific Terms of Use ：
有特別規定
本生物材料僅限使用於學術研究。寄存者對於分讓申請人使用本材料 所獲得之研究成果，不主張任何專利、智慧財產權及其他財產權
DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of BIOLOGICAL RESOURCE for academic research purpose.
分讓申請人公開發表使用本材料所獲得之論文或其他研究成果時，應引用下述已發表之論文： Cdk12 and Cdk13 regulate axonal elongation through a common signaling pathway that modulates Cdk5 expression (PubMed ID: 24999027).
Should the use of this material result in one or more scientific
publication(s) the recipient agrees to cite the paper(s)： Cdk12 and Cdk13 regulate axonal elongation through a common signaling pathway that modulates Cdk5 expression (PubMed ID: 24999027).
Construct Map ：
 
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