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RMRC No.

RMRC13355

Order

Strain/Stock Designation

C57BL/6N-Grhl2^tm1cNarl/Narl

Status

SP| (Cryopreserved or freeze-dried sperm)

Availability

Level4

Pricing

International：1,530USD

Last Update Date

2018/11/23

Analysis Data

Description
Genes &
alleles
Phenotype
Health &
husbandry
References
Specific Term
and Conditions
Construct map

Species

：

laboratory mouse

Strain Type

：

COI (coisogenic strain),MSR (mutant strain)

Mutant Type

：

TM (Target Mutation)

Other Names

：

Background Strain

：

C57BL/6

Strain Description

：

1.	Top priority novel gene in IMPC list and has potential affected in Cardiovascular, Neurobiology Research and Reproductive Biology
2.	The targeting construct was electroporated into C57BL/6N embryonic stem (ES) cells.
3.	Derived from RMRC13354 C57BL/6N-Grhl2^tm1aNarl/Narl crossed to RMRC13219 C57BL/6N-Tg(pCAGGS-FLPe)15Narl/Narl.
4.	Exons from ENSMUSE00001251037toENSMUSE00001246353were replaced with LoxP-flanked cDNA of Grhl2.

Depositor

：

National Center for Biomodels, National Institutes of Applied Research

財團法人國家實驗研究院國家生物模式中心

：

bujiii@nlac.narl.org.tw

Allele Symbol	：	Grhl2^tm1cNarl

Allele Name	：	grainyhead like transcription factor 2, target mutation 1c, National Applied Research Laboratories

Allele Description	：






Strain of Origin	：	C57BL/6

Gene Symbol	：	Grhl2

Gene Name	：	http://www.informatics.jax.org/marker/MGI:2182543

Chromosome	：	15






Genotyping Method	：	Download
Genotyping NLAC	：

Research Application

：

Cardiovascular	Neurobiology Research
Reproductive Biology

Construction Technologies

：

Cre-lox system

Animal Health Reports	：

Colony Maintenance Breeding & Husbandry	：

Colony Maintenance Mating System	：	hetero/hemi x wild type

References

：

Specific Terms of Use

：

Construct Map

：